Now whilst some of their fans might think that is just their bad luck, and pine for a tie against one of the lesser sides left in the competition, it will at least give Aitor Karanka and his men the chance to raise their game and get to strut their stuff at a stadium they could well be visiting in the league next season if all goes to plan with their promotion aims.
The club are a strong outfit and while Arsenal are most people’s favourites, we would never put it past the Championship side to cause another upset and here are five ways we think they can do that.
Click on free scoring duo Kike and Bamford to see just how we think the Boro can gun down Arsenal.
Boro fans. Can you manage to make it another win in the FA Cup against a Premier League side? Let us know your thoughts below, become a guest blogger or tweet us @LaFootyettes.