Inter Milan are a huge name in world football and are coming on the back of two wins, and will want to make sure that they take at the very least an away goal back to the San Siro for the second leg.
Celtic meanwhile are just as confident and see their passage to the next round – but for that to happen, their key players will have to be in tip top form – and here are the five we think are the most crucial.
Click on Craig Gordon to see who else we think needs to shine for Celtic to take a good result to the San Siro.
Celtic fans. Who are you tipping to do the business for your side? Let us know your thoughts below, become a guest blogger or tweet us @LaFootyettes.