The Blues are flying high and are looking better and better with each passing game – and are on the back of their greatest ever Champions League victory against Maribor.
They may be without forwards Diego Costa and Loic Remy, but Chelsea fans will still be expecting all three points, yet with the likes of Angel Di Maria and Radamel Falcao, Manchester United will be on the attack – and be looking to put the Blues on the back foot.
With old pals Mourinho and Louis van Gaal set to face off, here are five ways we think Mourinho can get one over on his friend.
Click on Eden Hazard to see five ways we think Jose Mourinho can emerge victorious at Old Trafford.
Chelsea fans. Do you think Mourinho can lead you to a win even without your forwards? Let us know your thoughts below or tweet us @LaFootyettes.