Any forward worth their salt knows the Manchester United back line leaves a fair bit to be desired and Cisse will want to get on that score sheet.
Chris Smalling had one of his better games against Sunderland (not saying much we know) and will want to prove to manager Louis van Gaal that he does have a future in the Manchester United defence come next season.
Both sides will want the win and the first goal will be crucial – if Newcastle get it, their fans will back them and United will panic. If United get it, cover your ears because the Toon Army will not be happy.